Central Amazon Conservation Complex, Brazil - UNESCO World Heritage Site

 Place: Central Amazon Conservation Complex, Brazil 

Significance: Given that it's over 6 million hectares it doesn't make much sense to talk about weather or route. This is the largest part of the Amazon rainforest that is protected. There are all the plants and animals that you think of with the Amazon rainforest, including river dolphins, manatee, a giant endangered fish (arapaima), jaguar etc.  Often called the lungs of the earth - many other areas of the Amazon are being devoloped - where as this entire area is protected.

Images:

Anavilhanas National Park (from lacgeo.com)

River dolphin (from naturalworldheritagesites.com)